There's many things that we as humans try to amass and look for, but sometimes (or most times) they are not even close to what we need in our lives, in God's view. 
Peruse the 5 below, and pinpoint which thing(s) that is lacking in your life, and make a point to acquire it. 

1: The presence of God in our lives. Which denotes the Holy Spirit
Psalms 27:4 "One thing have I desired of the LORD, that will I seek after; that I may dwell in the house of the LORD all the days of my life, to behold the beauty of the LORD, and to enquire in his temple"

2. Be a genuine giver from the heart.. And not give a to impress/show off kind of person 
Mark 10:21 "Then Jesus beholding him loved him, and said unto him, One thing thou lackest: go thy way, sell whatsoever thou hast, and give to the poor, and thou shalt have treasure in heaven: and come, take up the cross, and follow me."
-the young rich man was not a genuine giver, he lacked a heart of surrender. 

3. Knowing God, listening from God, Studying & Understating, and embracing God's word.
Luke 10:41-42 " And Jesus answered and said unto her, Martha, Martha, thou art careful and troubled about many things. But one thing is needful: and Mary hath chosen that good part, which shall not be taken away from her.''
-Jesus advised Martha to be like Mary, who was seeking to know God more. Mary was always listening to Jesus's preaching. 

4. Acknowledge God's grace upon your life, His blessings, His goodness and mercies.

Acknowledge what He has done for you. Do this regardless of any threats, coarsement or negativity in your life. 
John 9:25 " He answered and said, Whether he be a sinner or no, I know not: one thing I know, that, whereas I was blind, now I see."

5. Don't carry baggage. Forgive, forget and forge ahead. Let loose and move forward, your blessings are not in the past. 
Phillipians 3:13-14 "Brethren, I count not myself to have apprehended: but this one thing I do, forgetting those things which are behind, and reaching forth unto those things which are before, I press toward the mark for the prize of the high calling of God in Christ Jesus."

Notes:

• Let nothing destruct you, 
• Do not allow your much servive to destruct you
• Let not your money and resources destruct you 
• Let not your past destruct you
• David refused to be destructed by his power and capacity
• The rich young man was destructed by his money (wealth) 
• The blind man did not allow fear and intimidation to destruct him
• Paul did not allow his past to destruct him
• Martha was a great serving woman, but she let her servive destruct her

One(or more)  of these things may be lacking in your life. That which lacks you should pursue and become a better follower of Christ to God's glory.

May God help us to identify and rectify the things we are lacking in our lives, so we may live in accordance to His will. 

In Jesus' name 
Amen!