A randomized, controlled trial performed in six different obesity clinics looked at the effects of leptin on 73 obese men and women. Researchers reported in The Journal of the American Medical Association that daily use of leptin led to a mean weight loss of 15 pounds in a 24-week treatment period. More than 95% of the lost weight was from body fat.

There was considerable variation in the amount of weight that individual subjects lost during the treatment. Subjects who took the highest daily doses of leptin also lost the most weight.

Studies show that colostrum’s natural enveloping of the leptin molecule and other potentially fragile peptides and proteins actually shepherds the compound through the gastrointestinal tract and into the bloodstream where it does the most good.

The word leptin comes from the Greek word leptos, meaning “thin.” This protein hormone, discovered in 1994, regulates body weight and metabolism. It is expressed predominantly by adipocytes, the fancy word for fat cells, and acts like a signal to the brain on the status of fat stores elsewhere in the body; the hypothalamus, it turns out, has leptin receptors where they attach to regulate food intake and body weight.

Leptin appears to lead to reduction in food intake and body weight.

Along with decreased food consumption, there is an increase in the body’s energy expenditure, which in turn leads to a loss of fat tissue mass and an increase in lean muscle.

Researchers discovered in 2000 that when leptin works in conjunction with IGF-1 (insulinlike growth factor) and other cofactors found in colostrum, it can also shrink fat cells to normal size. (IGF-1 directs the body’s metabolic process, burning fat, balancing blood sugar and building lean muscle.)

When you diet with leptin supplements your wallet will get fat while you get thin! That’s the way diets are supposed to work.