Autumn's brilliant changing colors, stunning scenery along the St. Lawrence River and panoramic views of Nova Scotia and Eastern Canada's rugged coastline are reason enough to bookmark this itinerary. Plus, you can visit Prince Edward Island to sample its renowned seafood and make stops in vibrant cultural and culinary cities such as Montreal, Quebec City, Boston and New York City. But with a short window to view the height of the fall foliage in October and few lines offering the route, act quickly and lock in your plans now to book this trip for next year. Crystal Cruises, Oceania Cruises, Windstar Cruises and Princess Cruises offer this itinerary.