As the largest organ in the body in terms of both surface area and weight, the skin protects the body from the elements, regulates body temperature and fluid balance, and is an organ of sensation. All of these functions require proper blood flow. As blood flow decreases with age, a number of conditions can arise.

The benefits of blood flow and can be seen in the following ways:

• Healthy and radiant skin
• Even complexion
• Relief from dry skin
• Stretch mark reduction
• Decreased appearance of cellulite
• Reduction in appearance of spider veins
• Better circulation in hands and feet
• Reduced swelling and water retention

Study Protocol

Participants applied RENU 28 to one forearm twice each morning and twice each evening. Microcirculation in the skin on each arm was measured with a Laser Doppler Flowmetry (LDF) immediately after RENU 28 application, then again at one hour and three hours. Then, continuing the same morning/night applications, microcirculation was measured at 48 hours and again at 96 hours. The test was performed before RENU 28 application each morning so that results for that day would not reflect the latest application.

Results Summary

The following results were measured on participants’ forearms, comparing the arm where RENU 28 was applied to the control arm:

• 49% blood flow increase within 15 minutes of first application
• 34% blood flow increase one-hour post initial application
• 35% blood flow increase three hours post initial application
• 44% blood flow increase 48 hours into the study
• 55% blood flow increase 96 hours into the study