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Resveratrol may offer benefits in preventing or managing conditions associated with high blood sugar, such as metabolic syndrome or diabetes. Sirtris Pharmaceuticals, a company founded by Dr. David Sinclair, leader of the Harvard resveratrol study, is conducting a clinical trial to evaluate resveratrol’s effects in controlling blood sugar in patients with diabetes.
BioMarker Pharmaceuticals was recently recognized by the Wall Street Journal as a pioneer in the field of resveratrol research. Based in San Jose, California, BioMarker is an innovative research institute dedicated to the study of lengthening and enhancing the quality of human life. With support from the Life Extension Foundation, BioMarker is currently studying how resveratrol affects specific genes and cellular pathways to increase longevity. Leading these research efforts is Dr. Xi Zhao-Wilson, BioMarker’s chief scientist.
“BioMarker as a company is committed to conducting high-quality scientific research to support products that will help people live longer, healthier lives,” Dr. Zhao-Wilson told Life Extension. “The science in this area is young, but we are witnessing an explosion of information about how genes, proteins, specific molecular pathways, and normal and disease states are influenced by natural compounds like resveratrol. We believe this is just the tip of the iceberg, and that there will be tremendous advances in understanding the mechanisms underlying aging, and how these relate to diseases or maintenance of a disease-preventive state.”
Under Dr. Zhao-Wilson’s direction, BioMarker was one of the first companies to conduct a high-quality, controlled, single-dose study of resveratrol and grape extract in a large group of mice. BioMarker scientists compared mice given resveratrol and grape extract with a group of calorie-restricted mice. Using techniques of genetic analysis developed in collaboration with other research groups, the scientists then determined similarities and differences in gene expression in the groups of mice. Preliminary data analysis suggests that resveratrol’s benefits overlap with those of caloric restriction. Much like caloric restriction, resveratrol appears to offer tremendous promise in extending life span and improving quality of life.
According to Dr. Zhao-Wilson, “Our focus as a company is to pursue known and novel compounds . . . to understand the mechanisms underlying the disease-preventive and life-span-extending effects of interventions that mimic the beneficial effects of caloric restriction. Resveratrol . . . has been very helpful in elucidating some aspects of the total caloric-restriction picture.”
Article Produced By
Life Extension
https://www.lifeextension.com/magazine/2007/3/report_resveratrol/Page-02
(All these Articles can be read from this URL: )
https://markethive.com/group/ama/blog/the-role-of-resveratrol-in-achieving-optimal-health-p5
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