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This may come as a surprise to you, but no study has ever taken young adult humans, given them resveratrol, and followed them until they die to see how long they live. Human longevity is damned hard to study, which is why most longevity studies look at shorter-lived animals and then try to generalize those results to humans. A lot of skepticism is warranted here. First off, resveratrol has been studied on drosophilia, better known as fruit flies. Seriously. Fruit flies. Resveratrol was able to effectively prolong the lifespans of the fruit flies, but the effect varied a lot depending on the diet and gender of the flies. It’s hard to say what to make of this, since flies have very different diets and hormonal profiles than we do.
And then of course we have mice. Mouse studies have shown that resveratrol is able to provide substantial health benefits as the mice age, helping to preserve the mice’s motor functions, energy metabolism, and insulin sensitivity, and increasing median lifespan. The effects seem particularly strong when the mice are on a high-calorie diet, apparently because resveratrol mimics the effects of calorie-restricted diets. The benefits of resveratrol vary widely across species, with some seeing no benefit and others seeing an almost miraculous increase in lifespan. Due to the huge inter-species variability in results, it probably isn’t the best idea to extrapolate from animal to human studies.
In humans, the evidence suggests that resveratrol doesn’t increase life span per se, but does protect against many age-related health problems, such as osteoporosis, heart disease, and cognitive decline. There’s no direct evidence that resveratrol directly fights aging itself, although it might- might- increase median age somewhat by reducing some of the causes of premature death, and the increase in autophagy does suggest a possible anti-aging effect. In other words, resveratrol probably won’t let you live to 200, but it may well help you get past 100 and keep you out of the nursing home.
Article Produced By
John Fawkes
Hardcore evidence-based fitness and self-improvement
(All these Articles can be read with this URL: https://markethive.com/group/ama/blog/the-role-of-resveratrol-in-achieving-optimal-health-p5 )
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