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Resveratrol is a phenolic compound called a stilbene; plants produce these in response to injury, infection, fungal attack, or ultraviolet radiation. The very compounds that protect plants can also protect you. Most phenols, including stilbenes like resveratrol, are brightly colored, aromatic, and good for your health. Most stilbenes come from berries and grapes. They have strong antioxidant benefits, counteracting the daily "oxidative stress" that damages cells. Resveratrol, one stilbene compound, promotes bone, cardiovascular, and liver health. This unique nutrient also supports healthy aging, improves cognitive function, and normalizes hormone production.
Resveratrol exists primarily in two forms, a trans and a cis form. These forms are isomers — compounds with the same number and types of atoms but arranged in different structures. Cis and trans isomers, specifically, have atoms joined in the same order, but in a slightly different geometric configuration. That change makes cis isomers polar — carrying an electrical charge — and water-soluble, and trans molecules non-polar and fat-soluble. This gives them quite different properties, including bioavailability — essentially, the degree and rate at which your body absorbs them after going through the digestive system, liver, and bloodstream. Below, we break down the differences plus describe a third form.
Because trans-resveratrol is fat-soluble, it binds to lipoproteins (fat-containing proteins), which allows it to easily cross cell membranes. However, the body metabolizes and eliminates it quickly, so its bioavailability is relatively low at around 25 percent — but higher than cis-resveratrol.
A double bond isomer of trans-resveratrol, this molecule is polar and soluble in water, so it less easily enters cells and is less easily used by the body. You will sometimes find it as a filler in poor quality, less pure supplements.
This form is found in wine, but also in your gut after you consume trans-resveratrol. The probiotic microbes in your digestive tract interact with trans-resveratrol, metabolizing it into dihydro-resveratrol.
Article Produced By
Edward Group
Founder of Global Healing Center
Dr. Group centers his philosophy around the understanding that the root cause of disease stems from the accumulation of toxins in the body and is exacerbated by daily exposure to a toxic living environment. He believes it is his personal mission to teach and promote philosophies that produce good health, a clean environment, and positive thinking. This, he believes, can restore happiness and love to the world.
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