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In a cellular model of leucocytes (RBL-2H3 cells), it has been observed that resveratrol at 15 μM has an antiallergenic effect by decreasing the β-hexosaminidase activity.
In human mesenchymal stem cells, resveratrol promotes a spontaneous osteogenesis, activating genes such as osteocalcin and RUNX2. It also prevents adipogenesis by repressing the expression of some genes such as PPARγ2 and leptin, suggesting beneficial effects of resveratrol on bone regeneration.
Resveratrol has been shown to have beneficial effects on experimental diabetes. It improves the health status of diabetic rats induced with streptozotocin, by enhancing the energy metabolism and reducing protein breakdown.
Article Produced By
Neelam Khaper
Academic Editor:
Department of Physiology, Faculty of Medicine, University of Valencia, INCLIVA, Blasco Ibáñez Avenue 15, 46010 Valencia, Spain.Department of Physiotherapy, Faculty of Physiotherapy, University of Valencia, Gascó Oliag Street 5, 46010 Valencia, Spain.Sports Research Centre, Miguel Hernández University of Elche, University Avenue, s/n, 03202 Elche, Alicante, Spain.
*J. Gambini: se.vu@inibmag.naujAcademic Editor: Neelam Khaper
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4499410/
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